• Receive Free Newsletters
• Join a Community
Search Tips
news channel

•  Main
•  Top Stories
•  Cancer Center
•  HIV Center
•  Seniors Center
•  Allergy Center
  Consumer Health Information
  Dr. Dean Edell

    Special Offers
  Top Features
 •  Eczema
 •  Joint Pain
 •  Mental Health
 •  Digestion
 •  Circumcision
 •  Check Doctor Quality
 •  Compare Nursing Homes
Dr. Dean Specials
 •  Cruise with Dr. Dean Edell aboard the m/s Silver Cloud!
 •  Books and Tapes
  Health Encyclopedia
  3D Interactive Human Atlas
  Fit or Fat: Nutrition & Exercise
  Health Videos
  Best Doctors
  Cool Tools
  Health Profiles
  My Health Page
  Topic Centers
  Contact Us
  Privacy Policy
  People's Pharmacy: Drugs & Herbs
  Drug Search

Get the latest health news in your e-mail for FREE!
Sign Up!

Join the conversation:
• People's Pharmacy
• Parenting Place
• Relationships

  • E-mail this to a friend    • Print This Article

Circumcision may Prevent HIV Spread


(Ivanhoe Newswire) -- Previous research has shown circumcised men are less likely to be infected with HIV, and a new study helps explain why.


British researchers examined tissue samples from nine specimens of human foreskin. They found each sample contained cells expressing the protein DC-SIGN, which contains receptors that make it easier for HIV to enter cells, indicating foreskin may play a key role in disease transmission.

Researchers say their study was limited due to a lack of availability of suitable tissue. They write, "Biopsies of the penis are rarely taken, and most studies to date have used material from circumcisions. However, if human tissue were available, population studies correlating levels of DC-SIGN expression in the penis with HIV transmission rates could provide crucially important data." They say these types of studies should be performed in both circumcised and uncircumcised men.

HIV is a virus that infects and destroys T-cells in the immune system. According to the Centers for Disease Control and Prevention, there are between 800,000 and 900,000 people living with HIV.

Authors of the study say their results suggest that the human foreskin is important in mediating the sexual transmission of HIV. They conclude, "We suggest that DC-SIGN may contribute to HIV transmission in the foreskin by enabling the infection of permissive cells."

This article was reported by Ivanhoe.com, who offers Medical Alerts by e-mail every day of the week. To subscribe, go to: http://www.ivanhoe.com/newsalert/.

SOURCE: Journal of Clinical Pathology, 2004;57:77-78

Last Updated: January 05, 2004

Related 3D Interactive Human Atlas
   Pulled Groin Muscle
   Benign Prostate Hyperplasia
   Penile Implants
   Prostate Cancer
   Hair Loss

Related Articles
• Alzheimer's Risk in Men Tied to Low Testosterone
• Heart Patients Want More From Their Doctors
• Erectile Dysfunction May Signal Heart Disease
• Clothes Make the Doctor
• Adult Asthma Differs From Childhood Asthma

Related Videos
• Alternative To Vasectomy
• Better Prostate Cancer Test
• Estrogen For Men
• Fertility Test For Men
• Improved Prostate Treatment
• New Male Contraception
• Part1 Improving Patient Safety
• Part2 Hospitals Taking Action
• Part3 Tort Reform: The Solution Or Punishment
• Patch Up Your Love Life
• Predicting Prostate Cancer
• Prostate Cancer Prevention
• Prostate Cancer Protection
• Prostate Cancer Vaccine
• Prostate Laser
• Prostate Problem Vaporized
• Sci-Fi Medicine
• Ultrasound For Prostate Cancer
• Vitamin D For Prostate Cancer

Related Encyclopedia
• aging changes in the male reproductive system
• anorchia
• Balanitis
• Benign prostatic hyperplasia
• chancroid
• Chlamydia
• Chlamydia - female
• Chlamydial urethritis - male
• Chronic urethritis
• curvature of the penis
• drugs that may cause impotence
• Epididymitis
• Esophagitis herpes
• Genital warts
• Gonococcemia (Disseminated)
• gonorrhea - female
• Gonorrhea - Male
• Herpes Genital (genital Herpes simplex)
• Herpes labialis (oral Herpes simplex)
• Herpes simplex
• Herpes Zoster
• herpetic stomatitis
• hydrocele
• Hypogonadism
• Kegel exercises
• Neuralgias
• Orchitis
• over-the-counter birth control
• Paraphimosis
• Pelvic inflammatory disease (PID)
• Pharyngitis, gonococcal
• prostate cancer
• Prostatitis; acute
• Prostatitis; chronic
• Prostatitis; non-bacterial
• Retrograde ejaculation
• Scrotal masses
• support group - BPH
• support group - incontinence
• support group - prostate cancer
• Syphilis
• Syphilis - primary
• Syphilis - secondary
• Testicular failure
• testicular infection or torsion
• Testicular torsion
• Tinea cruris
• Trichomoniasis
• Urethritis
• Varicocele


From our sponsors:





We subscribe to the HONcode principles
of the Health On the Net Foundation

Please visit our partner sites:
     http://www.depressionissues.com/     http://www.digestivefacts.com/     http://www.alzheimersissues.com/
     http://www.bipolardepressioninfo.com/     http://www.liverfacts.com/     http://www.allergy-information.com/

Click here for other links.

By using this service, you accept our Terms of Use . Please read them. The consumer health information on HealthCentral.com is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen.